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The 2021 AIFA Cup of Nations was the 22nd AIFA Cup of Nations, the region championship for national football teams organized by AIFA. It took place in Slovertia and Berique as joint-hosts from 29 July to 10 August, after the countries were awarded host rights in 2020. It is the fourth Cup of Nations to be hosted by more than one country.
The tournament consisted of 32 teams from six different confederations, with Slovertia and Berique automatically qualifying due to hosting the event. The Scottopian Isles were crowned the champions after winning the final against Great Nortend 4-1 after regulation. It is Scottopia's first title, the second nation from Hesperidesia to win the competition.
In March 2021, AIFA announced the prices for all participating nations. Each qualified team received $1 million before the competition to cover preparation costs with each team receiving at least $7 million in prize money. This edition's total prize pool was $367 million, $35 million greater than the prize pool of the previous tournament.